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pentobarbital will decrease the level or impact of quetiapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will minimize the extent or result of brexpiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Double brexpiprazole dose over 1-two months if